Sources

Where the evidence comes from.

Symmathy queries each source through its public API or licensed gateway. Every claim shown in a summary or chat answer links back to its origin record.

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PubMed / MEDLINE

The US National Library of Medicine's flagship index. 37M+ citations across every major biomedical journal back to 1966, with structured MeSH subject indexing. The default first stop for clinical literature in English.

US · curated

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Europe PMC

European mirror of MEDLINE plus the full PubMed Central open-access archive and the major preprint servers (bioRxiv, medRxiv, ChemRxiv). Often surfaces full-text links PubMed alone won't.

EU + preprints · curated

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Cochrane Library

The gold-standard source for systematic reviews and meta-analyses. Cochrane reviews synthesize all available trials on a clinical question using rigorous, pre-registered methodology — the top of the evidence pyramid.

International · highest evidence tier

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ClinicalTrials.gov

The world's largest registry of clinical studies, run by the US NIH. 490k+ trials with protocols, eligibility criteria, sponsor, recruitment status, and (when posted) results. Essential for spotting unpublished or in-progress evidence.

Global trial registry

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J-STAGE

Japan Science and Technology Agency's platform for Japanese-published biomedical research. Covers thousands of society journals — much of which never reaches PubMed — with English abstracts.

Japan & Asia · curated

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LILACS

BVS / BIREME's regional health sciences index. The authoritative source for Brazilian, Argentine, Mexican, Chilean, and Caribbean medical research, including tropical disease and public health work absent from US/EU databases.

Latin America & Caribbean · curated

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DOAJ

Directory of Open Access Journals — a vetted whitelist of legitimate OA journals worldwide. Strong coverage of African, Asian, and Latin American medical research from journals that pass editorial-quality screening.

Open access · curated

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HAL

France's national open archive, run by CNRS. The primary index for French and francophone life-sciences research, including INSERM, Institut Pasteur, and university medical centers — much of which is not indexed in PubMed.

France & Europe · curated

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OpenAlex

Open replacement for Microsoft Academic. ~250M scholarly works with the broadest non-Western coverage available — Chinese, Thai, Israeli, Middle-Eastern, and African journals. Unfiltered, so quality varies; use alongside curated sources.

Global · aggregated

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CrossRef

The DOI registration agency for almost every academic publisher on Earth. Used here as the broadest possible metadata net — surfaces papers from publishers that don't appear in any disciplinary index, and helps deduplicate hits across sources.

Cross-publisher · aggregated

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ThaiJO

Thai Journals Online — the TCI national platform hosting Thai-published biomedical research, much of which never appears in PubMed or OpenAlex. ThaiJO has no unified search API, so Symmathy harvests its per-journal OAI-PMH feeds nightly into a local index, scoped to TCI health-sciences journals.

Thailand · harvested locally

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KoreaMed

The Korean Association of Medical Journal Editors' index of major Korean biomedical journals — JKMS, JKMA, KJIM, KJFM, and ~250 others. Most records link out to open-access full text via KoreaMed Synapse. Queries are translated into Korean to surface records whose metadata is only in Korean.

Korea · curated (KAMJE)

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